Hypodermic Syringe Testing

A hypodermic syringe is a small syringe used with a hollow hypodermic needle for injection of material into or beneath the skin. The vast majority of syringes are disposable, single-use and manually-operated. It's important to evalute the plunging movement, pull out forces and flow characteristices to ensure the syringes's plunging motion is consistent.

What is ISO 7886-1?

ISO 7886-1 tests confirm smooth and consistent operation of the plunger when administering drugs from the syringe.

What is ISO 8537?

ISO 8537 is a test of sterile single-use syringes, with or without needle, for insulin. Mechanical tests are done to prove performance, including ensuring freedom from air and liquid leakage past the piston and testing nozzle/hub and needle/barrel unions. Also tests include plunger movement and pull out forces and flow characteristics.

What are the application requirements mentioned in the standards?

The ISO 7886-1 procedure uses the test machine to compress and expel water from syringes while measuring the force to move the syringe piston.

• Depress the piston at a constant speed of 100 mm/min (4 in/min)
• Measure and report initial, mean, and maximum force levels
• Forces can approach 100 N (20 lbf)

What are the common hypodermic syringe testing measurements?

• Breakaway force measures the initial (peak) force required to begin plunger movement
• Glide force is the force required to keep it moving, to continue depressing the plunger
• Liquid leakage of the plunger is also important
• Plunger performance is a measure of the minimum, the maximum and mean forces needed during the plunger stroke